Isaiah was born in 1977 and raised at the San Filipe Pueblo in New Mexico. Isaiah grew up helping his father, Raymond Twinhorse, an accomplished silversmith, create and sell jewelry. He started out selling his bracelets, rings, earrings and pendants in Santa Fe on the plaza, at the Heard Museum show and Santa Fe Indian Market where he still exhibits and sells.
Isaiah has forged his own jewelry making path like no other Native American artist. He works for himself making heavy-gauge sterling-silver cuffs, bracelets, pendants, rings and earrings. All of his silver work is hand cut and with its heavy construction, strong lines and sharp angles, his art is equally at home in modern jewelry stores as it is in reservation trading posts. Isaiah works in 0 gauge, 1/2 gauge and 1 gauge silver. It can take him 16 hours to make a heavy bracelet.
- 2004 Southwest Intertribal Marketplace, Jackie Autry Purchase Prize Awards for his silver, wood and Leather bolo tie
- Santa Fe Indian Market-2nd Place-Jewelry